Qualitative & Quantitative Composition

Each uncoated tablet contains Atenolol I.P. 50mg and Indapamide I.P. 2.5mg

Dosage Form

Oral Tablets

Therapeutic indications

Anti hypertensive and anti anginal

Dosage and administration

As directed by physician

Contra-indications

Should not use if allergic to atenolol or indapamide or any of the other ingredients in the product. Atelol-D is contraindicated in sinus bradycardia, sinus node dysfunction, heart block > 1st degree, compensated cardiac failure, cardiogenic shock, bronchospastic diseases, peripheral vascular diseases, anuria, severe hepatic impairment. Also contraindicated during pregnancy .

Warnings and Precautions

While generally safe for use, but in case of compensated heart failure. variant angina, acute MI, DM; peripheral vascular disorders; hepatic and renal dysfunction; elderly patients, children, pregnancy, lactation, fluid or electrolyte imbalance, hyperuricaemia, and lupus erythematosus.

Drug interactions

Decreased effect with aluminum and calcium salts, barbiturates, cholestyramine, NSAIDs, ampicillin,rifampicin. Additive effect with other antihypertensive agents and diuretics. Increased chance of hypokalaemia with corticosteroids, corticotropin and amphotericin. Potentially Fatal: Increased risk of lithium toxicity. Hypokalaemia enhances digitalis toxicity with cardiac gycosides.

Pregnancy & lactation

Category D.

Undesirable effects/side effects

Drowsiness, dizziness, light-headedness, blurred vision, coldness of the hands and feet, tired muscles, slowed heartbeats, sleep disturbances, dry mouth, nausea and vomiting, diarrhoea, constipation and abdominal cramps, skin rashes and/or dry eyes, weakness, fatigue, agitation, nervousness, anorexia, orthostatic hypotension, palpitations, hypokalaemia, hyponatraemia, and metabolic alkalosis.

Overdose

According to toxixity studies, the most important signs to be expected following acute overdose of Atelol-D are lethargy, sinus pause, bradycardia, hypotension, bronchospasm, hypoglycaemia, nausea, vomiting, weakness, GI disorders, and electrolyte imbalance.

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