Effect of prophylactic HEPATOGARD treatment on the incidence of hepatotoxicity in patients receiving anti – tuberculosis drugs

Article published in The Bombay Hospital Journal (Vol.34, No. 4, 1992, PP. 35-40)


In a double blind placebo controlled trial, 205 patients suffering from pulmonary tuberculosis receiving isoniazid, rifampicin, ethambutol and streptomycin were studied for effect of simultaneous administration of Hepatogard 3 Tablets 3 times a day during 1st two months of intensive therapy on the incidence of hepatotoxicity and clinical morbidity. No patients in drug treated group developed jaundice whereas one patient from controls developed jaundice. Overall incidence of abnormalities in liver function tests was low, but more number of patients in controls tended to record abnormal values than the drug treated patients.

Rapid restoration of appetite and feeling of well being was observed in drug treated group. Significant differences in favor of drug treatment were observed in the pattern of weight gain at the end of 8 weeks of treatment. No serious adverse effects attributable to Hepatogard treatment were observed. 

Clinical trial of HEPATOGARD in acute viral hepatitis

Article published in The Indian Practitioner (Vol. XLVI, Feb 1993, No. 2, PP. 141-151)


In a double blind placebo controlled trial, Hepatogard, a herbal formulation was evaluated in 62 patients of acute viral hepatitis. The clinical parameters viz., anorexia, nausea-vomiting, malaise, icterus, liver tenderness and hepatomegaly decreased markedly on the drug as compared to the placebo. The total serum bilirubin was elevated in the placebo group at the end of four days while during the same period, total serum bilirubin values in Hepatogard group dropped.

The difference between the placebo and the drug was significant (P < 0.005). The decline continued to be significant for next three weeks. Similar significant decline in serum transaminase values was observed. No serious adverse effects were observed.

How Digital Transformation Is Affecting The Pharma And Healthcare Industry?

Digitalization is the new buzzword. It touches each and every aspect of our lives. How is it possible that the pharma and healthcare industry remains unaffected by it?

In fact, being a technology-driven industry, it gets the most benefits of digital transformation.

There are digital modes for better patient care. There are people willing to receive treatment and healthcare using the digital platform.

Every day, there are new modes of communication and apps available to users, and new technologies are being launched.

These advancements will start a new era that will lead to a new phase in the history of healthcare. Want to know about some points that underline the digital transformation? Read the blog further.

Changing the role of patients in the treatment

Digital transformation makes patients more active in the treatment process nowadays.  Earlier, the person had to fix an appointment with the doctor while seeking treatment for an ailment. He used to follow the instructions and administer the drugs prescribed.

With digitization, patients go prepared by doing online research. They match the symptoms and conditions. They talk to others who developed similar symptoms or problems.

Some try to device the cure as well.

Also, people are concerned about their fundamental rights. Also, people have much higher expectations from professionals than ever before.

Patients have better accessibility

The availability of the data is humongous, and it is increasing with every passing day. The days are gone when medical information was limited to journals, and it was restricted to limited forums.

Earlier, patients were disclosed information on a need basis only.

The digital revolution removes all the secrecy. Every bit of information is available to everyone at a click. People can find everything they wish by hitting a button. They can compare drugs and find a better alternative.

And it is all possible without spending a dime!

Personalized health tracking

People are health conscious today. The physicians also know it well. Hence, doctors suggest the patients these healthcare apps.

What is the aim of these apps? They make things simple for both doctors as well as patients. It is user-friendly, and convincing way of getting medical services and access to healthcare information.

It opens more communication channels

Digital presence opens various social media platforms, emailers, and hospital websites to connect to their healthcare specialists.

They can have online access to their medical records as well.

All these things revolutionize the pharma and healthcare industry.

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